Sequence: SHGRITFAYFAN
| Experiment Id | EXP002493 |
|---|---|
| Paper | Delivery System Targeting Hemagglutinin of Influenza Virus A to Facilitate Antisense-Based Anti-H1N1 |
| Peptide | HA-binding peptide HABP / H17 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | no |
| Label Confidence | medium |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | Not clearly specified in main text |
| Mixing Ratio | |
| Formulation Format | Covalent peptide-ODN conjugate |
| Formulation Components | HABP peptide + PROP5 ODN via EMCS linker |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | A549 cells infected with influenza A/FM/1/86 (H1N1) |
| Animal Model | |
| Administration Route | |
| Output Type | Antiviral functional effect |
| Output Value | Main text states PROP5-HABP also showed significant inhibitory effect on IAV replication in vitro; detailed data are in supplemental figures not included here |
| Output Units | |
| Output Notes | Included because the main text reports another HABP-conjugated ODN cargo with in vitro anti-IAV activity; label confidence is medium because quantitative details are only referenced as supplemental figures. |
| Toxicity Notes | No specific toxicity issue reported for PROP5-HABP in the main text. |
| Curation Notes |