Sequence: H2N-Cys-(His)2-(Arg)4-(His)2-Cys-COOH
| Experiment Id | EXP000014 |
|---|---|
| Paper | Disulfide crosslinked stearoyl carrier peptides containing arginine and histidine enhance siRNA upta |
| Peptide | CH2R4H2C |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | peptide/siRNA electrostatic complex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | S-180 sarcoma cells |
| Animal Model | |
| Administration Route | |
| Output Type | VEGF secretion (ELISA) |
| Output Value | Significant VEGF reduction vs naked siRNA |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |