Sequence: KKALLAHALHLLALLALHLAHALKKA
| Experiment Id | EXP000022 |
|---|---|
| Paper | Poly(lactic acid) nanoparticles and cell-penetrating peptide potentiate mRNA-based vaccine expressio |
| Peptide | LAH4-L1 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP/mRNA polyplex or PLA-NP/CPP/mRNA nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | DC2.4 cells; primary human moDCs |
| Animal Model | |
| Administration Route | |
| Output Type | protein expression (eGFP, gag), DC activation |
| Output Value | Robust expression only for LAH4-L1 |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |