Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide (2019)
Sequence: PEG12-KLLLLKLLLLKLLLLKLLLLK
| Experiment Id | EXP000050 |
|---|---|
| Paper | Effective mRNA pulmonary delivery by dry powder formulation of PEGylated synthetic KL4 peptide |
| Peptide | PEG12KL4 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | peptide/mRNA electrostatic complexes; dry powder (SD, SFD) |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | A549; BEAS-2B lung epithelial cells |
| Animal Model | |
| Administration Route | |
| Output Type | luciferase / EGFP expression |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |