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EXP000052

Paper

Self-assembly of amphiphilic phospholipid peptide dendrimer-based nanovectors for effective delivery of siRNA therapeutics in prostate cancer therapy (2020)

Peptide

DSPE-KK2

Sequence: DSPE-dendritic Lys2

RNA

siRNA

All experiment fields

Experiment Id EXP000052
Paper Self-assembly of amphiphilic phospholipid peptide dendrimer-based nanovectors for effective delivery
Peptide DSPE-KK2
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence
In Vitro Functional Effect yes
Endosomal Escape Evidence yes
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format Amphiphilic phospholipid peptide dendrimer (AmPPD) nanoparticles
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells PC-3 prostate cancer cells
Animal Model
Administration Route
Output Type Hsp27 knockdown, migration/invasion inhibition
Output Value
Output Units
Output Notes
Toxicity Notes
Curation Notes