Sequence: DSPE-dendritic Lys2
| Experiment Id | EXP000054 |
|---|---|
| Paper | Self-assembly of amphiphilic phospholipid peptide dendrimer-based nanovectors for effective delivery |
| Peptide | DSPE-KK2 |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | Amphiphilic phospholipid peptide dendrimer (AmPPD) nanoparticles |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | PC-3 prostate cancer xenograft (BALB/c nude mouse) |
| Administration Route | intravenous injection |
| Output Type | tumor growth inhibition; Hsp27 silencing |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |