Sequence: YGRKKRRQRRR
| Experiment Id | EXP000056 |
|---|---|
| Paper | Efficient siRNA delivery using novel cell-penetrating peptide–siRNA conjugate-loaded nanobubbles and |
| Peptide | TAT |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP–siRNA conjugate encapsulated in ultrasound-responsive nanobubbles |
| Formulation Components | CPP–siRNA + PEGylated DSPC/DPPC lipids + perfluorobutane |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HT-1080 fibrosarcoma cells |
| Animal Model | |
| Administration Route | |
| Output Type | c-myc knockdown; apoptosis |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |