Sequence: (YARVRRRGPRR)2–dsRBD
| Experiment Id | EXP000061 |
|---|---|
| Paper | Highly efficient delivery of siRNA to a heart transplant model by a novel cell penetrating peptide–d |
| Peptide | Hph1–Hph1–dsRBD |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP–dsRBD/siRNA non-covalent complex (± CaCl2 condensation) |
| Formulation Components | Hph1–Hph1–dsRBD fusion protein + siRNA |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa; GFP-HeLa |
| Animal Model | |
| Administration Route | |
| Output Type | gene knockdown (GFP, GAPDH) |
| Output Value | Up to ~98% GFP knockdown; >70% GAPDH knockdown |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |