Peptide-mediated delivery of therapeutic mRNA in ovarian cancer (2019)
Sequence: Stearyl-AGYLLGSRRDLARALRRHLALRL
| Experiment Id | EXP000079 |
|---|---|
| Paper | Peptide-mediated delivery of therapeutic mRNA in ovarian cancer |
| Peptide | PepFect14 (PF14) |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP/mRNA nanoparticles |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | SKOV-3; SKOV-3 spheroids |
| Animal Model | |
| Administration Route | |
| Output Type | reporter protein expression |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |