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EXP000082

Paper

Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis (2022)

Peptide

CH2R4H2C

Sequence: Cys-His-His-Arg-Arg-Arg-His-His-Cys

RNA

siRNA

All experiment fields

Experiment Id EXP000082
Paper Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the trea
Peptide CH2R4H2C
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence
In Vitro Functional Effect
Endosomal Escape Evidence yes
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format PEG-PCL polymer micelles with CPP
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells Macrophage-related uptake studies (ex vivo tissue sections)
Animal Model
Administration Route
Output Type Cellular uptake and intracellular delivery
Output Value
Output Units
Output Notes
Toxicity Notes
Curation Notes