Sequence: Cholesterol–RRRRRRRRR
| Experiment Id | EXP000085 |
|---|---|
| Paper | Cholesteryl Oligoarginine Delivering Vascular Endothelial Growth Factor siRNA Effectively Inhibits T |
| Peptide | Chol-R9 |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | Chol-R9/siRNA electrostatic complexes |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | CT-26 subcutaneous colon adenocarcinoma allograft (BALB/c mouse) |
| Administration Route | intratumoral injection |
| Output Type | tumor growth regression; reduced VEGF and vascularization |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |