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EXP000093

Paper

The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptides (2017)

Peptide

NickFect57 (NF57)

Sequence: Stearyl-AGYLLGØØNLKALKALAKAIL-NH2

RNA

siRNA

All experiment fields

Experiment Id EXP000093
Paper The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptid
Peptide NickFect57 (NF57)
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence
In Vitro Functional Effect yes
Endosomal Escape Evidence yes
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format CPP/siRNA non-covalent nanoparticles
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells U87 MG-luc2 glioma cells
Animal Model
Administration Route
Output Type luc2 gene knockdown
Output Value Up to ~80% (PF6 highest)
Output Units
Output Notes
Toxicity Notes
Curation Notes