Sequence: Stearyl-AGYLLGKLLOOLAAAAALLOLL-NH2
| Experiment Id | EXP000097 |
|---|---|
| Paper | The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptid |
| Peptide | PepFect14 (PF14) |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP/siRNA non-covalent nanoparticles |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | U87 MG-luc2 glioma cells |
| Animal Model | |
| Administration Route | |
| Output Type | luc2 gene knockdown |
| Output Value | Up to ~80% (PF6 highest) |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |