Sequence: PFVYLI
| Experiment Id | EXP000099 |
|---|---|
| Paper | Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement the |
| Peptide | PFVYLI (PTD) |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | PTD–IVT-mRNA covalent conjugate |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | K-562 cells; β-thalassemia patient BM cells |
| Animal Model | |
| Administration Route | |
| Output Type | β-globin protein expression |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |