Sequence: WEARLARALARALARALARMALARALAL
| Experiment Id | EXP000117 |
|---|---|
| Paper | Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Antigen-Specific Immune Respons |
| Peptide | RALA |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | 7 µg mRNA |
| Mixing Ratio | |
| Formulation Format | Peptide–mRNA electrostatic nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | C57BL/6 mouse |
| Administration Route | intradermal |
| Output Type | immune activation |
| Output Value | Strong CD8+ T-cell proliferation and cytotoxic response |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |