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EXP000118

Paper

Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Antigen-Specific Immune Responses (2017)

Peptide

RGSG

Sequence: RGSGRGSGRGSGRGSG

RNA

mRNA

All experiment fields

Experiment Id EXP000118
Paper Arginine-Rich Peptide-Based mRNA Nanocomplexes Efficiently Instigate Antigen-Specific Immune Respons
Peptide RGSG
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration N/P = 10
Rna Concentration 1–2.5 µg mRNA
Mixing Ratio
Formulation Format Peptide–mRNA electrostatic nanocomplex
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells DC2.4
Animal Model
Administration Route
Output Type uptake only
Output Value
Output Units
Output Notes Endosomal trapping; no protein expression
Toxicity Notes
Curation Notes