Sequence: HHHHHHGOILLKALKALAKAIL
| Experiment Id | EXP000137 |
|---|---|
| Paper | Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in |
| Peptide | NF706-H61-C22 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | MR 20–40 |
| Rna Concentration | 25 nM (in vitro) |
| Mixing Ratio | CPP:siRNA MR30 optimal |
| Formulation Format | CPP–siRNA electrostatic nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | U87-Luc, CHO-GFP |
| Animal Model | |
| Administration Route | |
| Output Type | gene knockdown |
| Output Value | |
| Output Units | |
| Output Notes | Luciferase knockdown efficiency quantified |
| Toxicity Notes | |
| Curation Notes |