Sequence: HHHHYHHGOILLKALKALAKAIL
| Experiment Id | EXP000144 |
|---|---|
| Paper | Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in |
| Peptide | NF70-H6-C20 |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | MR30 |
| Rna Concentration | 1.6 mg siRNA/kg |
| Mixing Ratio | CPP:siRNA MR30 |
| Formulation Format | CPP–siRNA electrostatic nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | Balb/c mouse |
| Administration Route | IV |
| Output Type | gene knockdown |
| Output Value | ~60% Factor VII knockdown in liver |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |