Sequence: (Arg-Arg-Aib)5
| Experiment Id | EXP000155 |
|---|---|
| Paper | A helix foldamer oligopeptide improves intracellular stability and prolongs protein expression of th |
| Peptide | OligoArg-Aib |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | N/P = 2–4 |
| Rna Concentration | 0.5 µg mRNA |
| Mixing Ratio | N/P = 2 or 4 |
| Formulation Format | Oligopeptide–mRNA electrostatic polyplex |
| Formulation Components | ~200–650 nm (N/P dependent) |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HuH-7 |
| Animal Model | |
| Administration Route | |
| Output Type | protein expression (prolonged) |
| Output Value | |
| Output Units | |
| Output Notes | Sustained luciferase expression up to 72 h due to intracellular mRNA stabilization |
| Toxicity Notes | |
| Curation Notes |