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EXP000170

Paper

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo (2011)

Peptide

TP10

Sequence: AGYLLGKINLKALAALAKKIL-NH2

RNA

siRNA

All experiment fields

Experiment Id EXP000170
Paper Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and syst
Peptide TP10
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format Non-covalent TP10/siRNA complexes
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells Multiple cell lines
Animal Model
Administration Route
Output Type gene knockdown
Output Value
Output Units
Output Notes Efficient uptake but limited RNAi due to endosomal trapping
Toxicity Notes
Curation Notes