Sequence: AGYLLGKINLKALAALAKKIL-NH2
| Experiment Id | EXP000171 |
|---|---|
| Paper | Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and syst |
| Peptide | PF3 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | PF3/siRNA nanoparticles |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa, U2OS, HepG2 |
| Animal Model | |
| Administration Route | |
| Output Type | gene knockdown |
| Output Value | |
| Output Units | |
| Output Notes | Improved uptake; RNAi enhanced only with chloroquine |
| Toxicity Notes | |
| Curation Notes |