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EXP000172

Paper

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo (2011)

Peptide

PF5

Sequence: AGYLLGKINLKALAALAKKIL-NH2

RNA

siRNA

All experiment fields

Experiment Id EXP000172
Paper Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and syst
Peptide PF5
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect yes
Endosomal Escape Evidence yes
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format PF5/siRNA nanoparticles
Formulation Components
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells HeLa, U2OS
Animal Model
Administration Route
Output Type gene knockdown
Output Value
Output Units
Output Notes Efficient RNAi in serum-free conditions only
Toxicity Notes
Curation Notes