Sequence: AGYLLGKINLKALAALAKKIL-NH2
| Experiment Id | EXP000174 |
|---|---|
| Paper | Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and syst |
| Peptide | PF6 |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | PF6/siRNA nanoparticles |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | Mouse (systemic delivery) |
| Administration Route | IV |
| Output Type | in vivo gene knockdown |
| Output Value | Up to ~75% knockdown in liver, kidney, lung |
| Output Units | |
| Output Notes | |
| Toxicity Notes | No acute toxicity or inflammation |
| Curation Notes |