Sequence: R8–dodecyldiamine (mono amphiphile)
| Experiment Id | EXP000176 |
|---|---|
| Paper | HA-Modified R8-Based Bola-Amphiphile Nanocomplexes for Effective Improvement of siRNA Delivery Effic |
| Peptide | R8-monobola |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | R8-monobola/siRNA nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | 4T1 breast cancer cells |
| Animal Model | |
| Administration Route | |
| Output Type | Bcl-2 protein knockdown |
| Output Value | |
| Output Units | |
| Output Notes | ~67% Bcl-2 silencing; lower uptake vs bibola |
| Toxicity Notes | |
| Curation Notes |