Sequence: R8–dodecyldiamine–R8 (bola amphiphile)
| Experiment Id | EXP000177 |
|---|---|
| Paper | HA-Modified R8-Based Bola-Amphiphile Nanocomplexes for Effective Improvement of siRNA Delivery Effic |
| Peptide | HA–R8-bibola |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | HA–R8-bibola/siRNA nanocomplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | 4T1 tumor-bearing Balb/c mice |
| Administration Route | IV (tail vein) |
| Output Type | tumor growth inhibition |
| Output Value | ~70% tumor inhibition; strong Bcl-2 silencing |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |