Sequence: Fluorinated poly(L-lysine) peptide dendrimer
| Experiment Id | EXP000183 |
|---|---|
| Paper | Highly Efficient and Safe Delivery of VEGF siRNA by Bioreducible Fluorinated Peptide Dendrimers for |
| Peptide | BFPD-11 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | BFPD-11/siRNA polyplex |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa |
| Animal Model | |
| Administration Route | |
| Output Type | VEGF knockdown / proliferation inhibition |
| Output Value | |
| Output Units | |
| Output Notes | Up to ~65% VEGF silencing; BFPD-12 highest |
| Toxicity Notes | |
| Curation Notes |