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EXP000193

Paper

Development and Characterization of High Efficacy Cell-Penetrating Peptide via Modulation of the Histidine and Arginine Ratio for Gene Therapy (2021)

Peptide

HALA3

Sequence: WEAHLAHALAHALARHLARALARALRACEA

RNA

pDNA / siRNA

All experiment fields

Experiment Id EXP000193
Paper Development and Characterization of High Efficacy Cell-Penetrating Peptide via Modulation of the His
Peptide HALA3
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect yes
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format Non-covalent peptide–nucleic acid nanocomplex
Formulation Components <200 nm
Size Nm
Zeta Mv 25.00
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells HeLa; HEK-293T; A549
Animal Model
Administration Route
Output Type transfection / gene silencing
Output Value
Output Units
Output Notes HALA2 shows highest pDNA expression and GAPDH silencing; others moderate
Toxicity Notes
Curation Notes