Sequence: (2-Azido-)GIGAVLKVLTTGLPALISWIKRKRQ-OH
| Experiment Id | EXP000196 |
|---|---|
| Paper | mRNA Polyplexes with Post-Conjugated GALA Peptides Efficiently Target, Transfect, and Activate Antig |
| Peptide | Melittin |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | PPx-Melittin (peptide-modified mRNA polyplex) |
| Formulation Components | ~150–200 nm |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | DC2.4 dendritic cells; RAW264.7 macrophages; D1 dendritic cells |
| Animal Model | |
| Administration Route | |
| Output Type | mRNA transfection / antigen presentation |
| Output Value | |
| Output Units | |
| Output Notes | Low to moderate transfection; limited endosomal escape |
| Toxicity Notes | |
| Curation Notes |