Sequence: Cys-His-His-Arg-Arg-Arg-Arg-His-His-Cys
| Experiment Id | EXP000202 |
|---|---|
| Paper | Anti-Metastatic Effects on Melanoma via Intravenous Administration of Anti-NF-κB siRNA Complexed wit |
| Peptide | CH2R4H2C |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | N/P 10 |
| Formulation Format | siRelA/MPEG-PCL-CH2R4H2C micelles |
| Formulation Components | ~50 nm |
| Size Nm | |
| Zeta Mv | 5.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | B16F10 melanoma cells |
| Animal Model | |
| Administration Route | |
| Output Type | migration suppression / gene silencing |
| Output Value | |
| Output Units | |
| Output Notes | Strong uptake; wound-healing assay shows migration inhibition without cytotoxicity |
| Toxicity Notes | |
| Curation Notes |