Sequence: RRRRRRRRR
| Experiment Id | EXP000250 |
|---|---|
| Paper | Unraveling mRNA delivery bottlenecks of ineffective delivery vectors by co-transfection with effecti |
| Peptide | Nona-arginine (R9) |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | very high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | 1–5 µM |
| Rna Concentration | ~107–214 ng per well |
| Mixing Ratio | Electrostatic complexation |
| Formulation Format | Peptide–mRNA nanoparticles |
| Formulation Components | R9 + mRNA |
| Size Nm | 86.00 |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | MC3T3-E1; HeLa; C5120 fibroblasts; hBMSC |
| Animal Model | |
| Administration Route | |
| Output Type | Protein expression |
| Output Value | No expression unless co-transfected with PF14 |
| Output Units | |
| Output Notes | Uptake occurs but endosomal escape insufficient |
| Toxicity Notes | Low toxicity alone |
| Curation Notes |