Sequence: PSP (CKRRMKNvocWKNvocKNvoc) + NGR
| Experiment Id | EXP000303 |
|---|---|
| Paper | Enhanced small interfering RNA delivery into cells by exploiting the additive effect between photo-s |
| Peptide | PSP/NGR-L |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | medium |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | Lipid formulation dependent |
| Rna Concentration | 200–300 nM |
| Mixing Ratio | Encapsulated in liposomes |
| Formulation Format | Peptide-modified liposome |
| Formulation Components | PSP/NGR-L |
| Size Nm | 95.00 |
| Zeta Mv | 1.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HT-1080; MCF-7 |
| Animal Model | |
| Administration Route | |
| Output Type | c-myc knockdown (qRT-PCR, Western blot) |
| Output Value | Measured |
| Output Units | |
| Output Notes | UV-pretreated PSP/NGR-L shows strongest knockdown and apoptosis |
| Toxicity Notes | UV exposure controlled; low carrier toxicity |
| Curation Notes |