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EXP000312

Paper

Glycopolymer–Cell-Penetrating Peptide (CPP) Conjugates for Efficient Epidermal Growth Factor Receptor (EGFR) Silencing (2022)

Peptide

ARP-P4

Sequence: KRRKRRRRRK_P4

RNA

siRNA

All experiment fields

Experiment Id EXP000312
Paper Glycopolymer–Cell-Penetrating Peptide (CPP) Conjugates for Efficient Epidermal Growth Factor Recepto
Peptide ARP-P4
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format polyplex
Formulation Components glycopolymer-ARP conjugate + siRNA
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells HeLa
Animal Model
Administration Route
Output Type EGFR knockdown
Output Value
Output Units
Output Notes Polyplex too stable; low knockdown
Toxicity Notes ~90% cell viability
Curation Notes