Sequence: CGRRMKWKK_pc_NGR_LP
| Experiment Id | EXP000316 |
|---|---|
| Paper | Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRN |
| Peptide | pcCPP |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | liposome |
| Formulation Components | pcCPP + NGR dual-modified liposomes |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | HT-1080 xenograft nude mice |
| Administration Route | intravenous |
| Output Type | tumor growth inhibition; gene silencing |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |