Sequence: CONH2-WEAKLAKALAKALAKHLA-NH2
| Experiment Id | EXP000325 |
|---|---|
| Paper | Cell Penetrating Peptides Functionalized siRNA Nanoparticles Knockdown HER Receptors in Breast Cance |
| Peptide | KALA |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | no |
| Peptide Concentration | |
| Rna Concentration | 200–600 nM |
| Mixing Ratio | |
| Formulation Format | nanoparticle |
| Formulation Components | methylated protamine + CPP + siRNA |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | BT474, SKBR3 |
| Animal Model | |
| Administration Route | |
| Output Type | uptake / complexation |
| Output Value | |
| Output Units | |
| Output Notes | Linear KALA characterized; no siRNA knockdown data |
| Toxicity Notes | >90% cell viability |
| Curation Notes |