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EXP000367

Paper

Oligohistidine and targeting peptide functionalized TAT‑NLS for enhancing cellular uptake and promoting angiogenesis in vivo (2018)

Peptide

REDV-TAT-NLS-H4

Sequence: REDV-YGRKKRRQRRR-PKKKRKV-HHHH

RNA

plasmid DNA

All experiment fields

Experiment Id EXP000367
Paper Oligohistidine and targeting peptide functionalized TAT‑NLS for enhancing cellular uptake and promot
Peptide REDV-TAT-NLS-H4
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect yes
Endosomal Escape Evidence yes
Peptide Concentration ≈40 µg/mL
Rna Concentration 3 µg per well
Mixing Ratio w/w 5
Formulation Format peptide/DNA complex
Formulation Components REDV-TAT-NLS-H4 + pZNF580
Size Nm 117.00
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells HUVECs
Animal Model
Administration Route
Output Type gene expression / angiogenic function
Output Value ↑ ZNF580 mRNA & protein, tube formation
Output Units
Output Notes Functional transfection in HUVECs
Toxicity Notes Low cytotoxicity (>80% viability)
Curation Notes