Sequence: REDV-YGRKKRRQRRR-PKKKRKV-HHHH
| Experiment Id | EXP000370 |
|---|---|
| Paper | Oligohistidine and targeting peptide functionalized TAT‑NLS for enhancing cellular uptake and promot |
| Peptide | REDV-TAT-NLS-H4 |
| Delivery Success Class | no |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | peptide/DNA complex |
| Formulation Components | REDV-TAT-NLS-H4 + pZNF580 |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | Pre-transfected HUVECs |
| Animal Model | male mouse subcutaneous Matrigel plug |
| Administration Route | subcutaneous (cells implanted) |
| Output Type | angiogenesis |
| Output Value | ↑ CD31+ microvessel structures |
| Output Units | |
| Output Notes | Ex vivo–transfected cells implanted (not in vivo delivery) |
| Toxicity Notes | No systemic toxicity reported |
| Curation Notes |