Sequence: GRKKRRQRRRGC
| Experiment Id | EXP000408 |
|---|---|
| Paper | Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of |
| Peptide | CS-PEG-TAT/siRNA |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | 2 µg/mL |
| Mixing Ratio | N/P ≈103 |
| Formulation Format | polymer-based nanoparticle |
| Formulation Components | Chitosan-PEG-TAT polymer + siRNA |
| Size Nm | 85.00 |
| Zeta Mv | 15.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | Mouse neuroblastoma Neuro2a cells |
| Animal Model | |
| Administration Route | |
| Output Type | cellular uptake / transfection |
| Output Value | High intracellular fluorescence; efficient uptake |
| Output Units | |
| Output Notes | In vitro nanoparticle optimization study |
| Toxicity Notes | Low cytotoxicity at optimal pH |
| Curation Notes |