RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA (2007)
Sequence: RQIKIWFQNRRMKWKK
| Experiment Id | EXP000491 |
|---|---|
| Paper | RNA targeting with peptide conjugates of oligonucleotides, siRNA and PNA |
| Peptide | Penetratin |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | 0.1–10 μM |
| Mixing Ratio | |
| Formulation Format | covalent CPP–RNA conjugate |
| Formulation Components | |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa, HepG2 |
| Animal Model | |
| Administration Route | |
| Output Type | gene knockdown / trans-activation inhibition |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |