Sequence: RGD
| Experiment Id | EXP000496 |
|---|---|
| Paper | Enhanced Lysosomal Escape of pH-Responsive Polyethylenimine–Betaine Functionalized Carbon Nanotube f |
| Peptide | RGD |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | 80 nM (in vitro) |
| Mixing Ratio | |
| Formulation Format | SWCNT–PEI–betaine–peptide nanocomplex |
| Formulation Components | SWCNT, PEI-betaines, peptide, siRNA, ±DOX |
| Size Nm | 250.00 |
| Zeta Mv | 25.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | A549, HeLa, 293T |
| Animal Model | |
| Administration Route | |
| Output Type | gene knockdown / uptake / apoptosis |
| Output Value | |
| Output Units | |
| Output Notes | |
| Toxicity Notes | Low carrier toxicity; DOX contributes toxicity |
| Curation Notes |