Sequence: RGD
| Experiment Id | EXP000497 |
|---|---|
| Paper | Enhanced Lysosomal Escape of pH-Responsive Polyethylenimine–Betaine Functionalized Carbon Nanotube f |
| Peptide | RGD |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | 1 mg/kg (siRNA) |
| Mixing Ratio | |
| Formulation Format | SWCNT–PEI–betaine–peptide nanocomplex |
| Formulation Components | SWCNT, PEI-betaines, peptide, siRNA, ±DOX |
| Size Nm | 250.00 |
| Zeta Mv | 25.00 |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | A549 tumor-bearing nude mice |
| Administration Route | intravenous |
| Output Type | tumor growth inhibition |
| Output Value | |
| Output Units | |
| Output Notes | Only BR2-modified system shows strong tumor suppression |
| Toxicity Notes | No major organ toxicity observed |
| Curation Notes |