Sequence: ac-GALFLGFLGAAGSTMGAWSQPKSKRKV-cya
| Experiment Id | EXP000671 |
|---|---|
| Paper | Cell-penetrating peptide and cationic liposomes mediated siRNA delivery to arrest growth of chronic |
| Peptide | MPG-DNLS |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | CR optimized (from prior work) |
| Rna Concentration | 200 nM |
| Mixing Ratio | reported optimal CR |
| Formulation Format | CPP/siRNA polyplex |
| Formulation Components | MPG-DNLS peptide + siRNA |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | K562 |
| Animal Model | |
| Administration Route | |
| Output Type | uptake control |
| Output Value | Uptake maintained at 4 °C (energy-independent) |
| Output Units | |
| Output Notes | Used as positive control for energy-independent translocation; no gene silencing data presented in this study. |
| Toxicity Notes | Not discussed |
| Curation Notes |