Sequence: Stearyl-octaarginine (R8)
| Experiment Id | EXP000756 |
|---|---|
| Paper | Development of a Novel Nanoparticle by Dual Modification With the Pluripotential Cell-Penetrating Pe |
| Peptide | R8 polyplex |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | N/P 3.0; siRNA:pDNA 1:2 |
| Formulation Format | Peptide–siRNA polyplex (intermediate) |
| Formulation Components | R8 + siRNA + plasmid DNA |
| Size Nm | 160.00 |
| Zeta Mv | 4.00 |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | B16-F1-luc |
| Animal Model | |
| Administration Route | Not applied as standalone delivery system |
| Output Type | Polyplex characterization |
| Output Value | Tight condensation; poor release |
| Output Units | |
| Output Notes | Strong condensation limits RNAi unless escape device added |
| Toxicity Notes | |
| Curation Notes |