Structural effects of oligomerization of arginine-rich peptides on cellular uptake and cytotoxicity (2016)
Sequence: RRRRRRRRR
| Experiment Id | EXP000777 |
|---|---|
| Paper | Structural effects of oligomerization of arginine-rich peptides on cellular uptake and cytotoxicity |
| Peptide | R9 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | no |
| Peptide Concentration | 1–10 μM |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP only (Alexa Fluor–labeled) |
| Formulation Components | R9-Alexa Fluor conjugate |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HeLa |
| Animal Model | |
| Administration Route | Cell incubation |
| Output Type | Cellular uptake and localization |
| Output Value | Low uptake; punctate endosomal localization |
| Output Units | |
| Output Notes | Serves as monomeric CPP control |
| Toxicity Notes | Low cytotoxicity |
| Curation Notes |