Sequence: RGGRLSYSRRRFSTSTGR
| Experiment Id | EXP001071 |
|---|---|
| Paper | Designing siRNA for silencing the human ERBB2 gene in cancer treatment: Evaluating intracellular del |
| Peptide | CPP-8 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | no |
| Label Confidence | medium |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | Electrostatic complex (in silico docking) |
| Formulation Components | Designed siRNA-3 + LMWP CPP (from CPPsite 2.0); docking performed with NPdock |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | |
| Animal Model | |
| Administration Route | |
| Output Type | Docking score (kcal/mol) |
| Output Value | -187.1 |
| Output Units | |
| Output Notes | Molecular docking of individual CPP with designed siRNA-3 (computational; no cellular assays). |
| Toxicity Notes | |
| Curation Notes |