Sequence: PFVYLI
| Experiment Id | EXP001634 |
|---|---|
| Paper | Structure-guided design of nucleosome-inspired nanoparticles for overcoming pulmonary barriers in fi |
| Peptide | P13 |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | N/P 4–20 (screen); representative imaging at N/P=12 |
| Formulation Format | peptide/siRNA complexes |
| Formulation Components | peptide + siRNA |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | A549 (6 h uptake/transfection screen) |
| Animal Model | |
| Administration Route | |
| Output Type | uptake / transfection efficiency |
| Output Value | |
| Output Units | |
| Output Notes | Flow cytometry screen across N/P ratios; functional knockdown not reported for these peptides. |
| Toxicity Notes | Cytotoxicity assessed on HBE135-E6E7 for selected peptides; see paper for details. |
| Curation Notes |