Sequence: PFVYLIRFHRFHRFHGGGSSSQLSRP
| Experiment Id | EXP001652 |
|---|---|
| Paper | Structure-guided design of nucleosome-inspired nanoparticles for overcoming pulmonary barriers in fi |
| Peptide | MNM |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | medium |
| In Vitro Functional Effect | yes |
| Endosomal Escape Evidence | yes |
| Peptide Concentration | |
| Rna Concentration | |
| Mixing Ratio | N/P=20 (reported for MNM nanoparticle formulations) |
| Formulation Format | peptide/nucleic acid nanoparticles |
| Formulation Components | MNM + nucleic acid |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HEK293T (and BMDCs for mRNA) |
| Animal Model | |
| Administration Route | |
| Output Type | reporter expression |
| Output Value | Reporter expression observed by microscopy; quantified by fluorescence (see supplementary figs). |
| Output Units | |
| Output Notes | |
| Toxicity Notes | |
| Curation Notes |