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EXP001959

Paper

Identification of a novel cell-penetrating peptide targeting human glioblastoma cell lines as a cancer-homing transporter (2015)

Peptide

R9 (nona-arginine) control CPP

Sequence: RRRRRRRRR

RNA

All experiment fields

Experiment Id EXP001959
Paper Identification of a novel cell-penetrating peptide targeting human glioblastoma cell lines as a canc
Peptide R9 (nona-arginine) control CPP
Delivery Success Class no
In Vivo Flag no
Uptake Confirmed yes
Label Confidence high
In Vitro Functional Effect no
Endosomal Escape Evidence
Peptide Concentration
Rna Concentration
Mixing Ratio
Formulation Format Peptide alone or peptide–cargo fusion (no RNA payload)
Formulation Components FITC-labeled peptides for uptake assays; p16 MIS fusion peptides for functional cargo delivery (apoptosis/pRB phosphorylation).
Size Nm
Zeta Mv
Model Scope in_vitro
Model Type in vitro
Cell Lines Or Primary Cells U87MG and U118MG (glioblastoma); other lines for selectivity panel (HeLa, HepG2, A549, PANC-1, etc.)
Animal Model
Administration Route
Output Type Uptake control
Output Value Strong but nonselective cell penetration (positive control).
Output Units
Output Notes Used for benchmarking peptide1 variants.
Toxicity Notes
Curation Notes