Identification of a Novel Cell-Penetrating Peptide from Human Phosphatidate Phosphatase LPIN3 (2012)
Sequence: RRKRRRRRK
| Experiment Id | EXP002025 |
|---|---|
| Paper | Identification of a Novel Cell-Penetrating Peptide from Human Phosphatidate Phosphatase LPIN3 |
| Peptide | LPIN (LPIN3-derived CPP) |
| Delivery Success Class | no |
| In Vivo Flag | yes |
| Uptake Confirmed | no |
| Label Confidence | high |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | 5 mg LPIN-EGFP per mouse |
| Rna Concentration | |
| Mixing Ratio | |
| Formulation Format | CPP–protein fusion |
| Formulation Components | LPIN peptide + EGFP |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | C57BL/6 mice |
| Administration Route | intraperitoneal |
| Output Type | tissue uptake |
| Output Value | Fluorescent signal detected in intestine, liver, kidney |
| Output Units | |
| Output Notes | Fluorescence microscopy of tissue sections 1–2 h post injection |
| Toxicity Notes | No toxicity reported |
| Curation Notes |