Sequence: INHVGGTGGAIMAPVAVTRQLVGS
| Experiment Id | EXP002063 |
|---|---|
| Paper | Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-Annulus-dT20 Conjugate |
| Peptide | β-annulus |
| Delivery Success Class | no |
| In Vivo Flag | no |
| Uptake Confirmed | yes |
| Label Confidence | high |
| In Vitro Functional Effect | no |
| Endosomal Escape Evidence | |
| Peptide Concentration | 450 µM (in vitro) |
| Rna Concentration | 1 µM |
| Mixing Ratio | dT20-SS-β-annulus : β-annulus = 1:9 |
| Formulation Format | Artificial viral capsid |
| Formulation Components | β-annulus + dT20-SS-β-annulus co-assembly |
| Size Nm | 52.00 |
| Zeta Mv | |
| Model Scope | in_vitro |
| Model Type | in vitro |
| Cell Lines Or Primary Cells | HepG2 cells |
| Animal Model | |
| Administration Route | |
| Output Type | reporter expression |
| Output Value | Minimal mCherry expression without CPP modification |
| Output Units | |
| Output Notes | Baseline capsid shows poor cellular delivery |
| Toxicity Notes | No toxicity reported |
| Curation Notes |