Sequence: GALFLGFLGAAGSTMGA-WSQ-PKSKRKV
| Experiment Id | EXP002066 |
|---|---|
| Paper | Efficient delivery of miR-122 to regulate cholesterol metabolism using a non-covalent peptide-based |
| Peptide | MPGΔNLS |
| Delivery Success Class | yes |
| In Vivo Flag | yes |
| Uptake Confirmed | yes |
| Label Confidence | medium |
| In Vitro Functional Effect | |
| Endosomal Escape Evidence | |
| Peptide Concentration | |
| Rna Concentration | 50 nM |
| Mixing Ratio | 20:1 (peptide:miRNA) |
| Formulation Format | Non-covalent peptide/miRNA complex |
| Formulation Components | MPGΔNLS + miR-122 |
| Size Nm | |
| Zeta Mv | |
| Model Scope | in_vivo |
| Model Type | in vivo |
| Cell Lines Or Primary Cells | |
| Animal Model | C. elegans |
| Administration Route | soaking |
| Output Type | phenotypic / metabolic regulation |
| Output Value | Efficient organismal uptake; functional miRNA activity inferred |
| Output Units | |
| Output Notes | Model organism validation of delivery |
| Toxicity Notes | No toxicity reported |
| Curation Notes |